Day: April 13, 2022

Novadiscovery announces Nature Communications paper on modeling the disruption to respiratory clinical trials due to mitigation measures against COVID-19

Model uses virtual populations and in silico trials to show impact on clinical trials and suggest adaptations to trial design

Lyon, France – 13 April 2022: Novadiscovery (NOVA), a leading health tech company using in silico clinical trials to predict drug efficacy and optimize clinical trial development, today announces the publication of a novel model of respiratory tract infections (RTI) in Nature Communications to address the uncertainties resulting from non-pharmaceutical interventions (NPIs) against COVID-19 on clinical trials. The paper was published in collaboration with NOVA’s partner OM Pharma.

François-Henri Boissel, CEO, NOVA said: “The pandemic and all related measures such as lockdowns seriously affected clinical trials in all indications but the impact of reduced viral transmission and resulting seasonal disease pattern disruption on respiratory trials was particularly marked. Our model provides vital information on whether trials will still meet their endpoints, how to interpret clinical relevance, and potential adaptations to statistical analyses and trial design – such as recruitment numbers – to maximise success and avoid delays in getting new treatments to patients.”

NOVA’s modeling approach is rooted in systems biology and quantitative systems pharmacology. The paper describes how the model was used to run in silico clinical trial simulations with OM Pharma’s OM-85 as prophylaxis for respiratory tract infection (RTI) in virtual populations and under various scenarios of reduced viral transmissions due to NPIs.

The results have led the paper’s authors to advocate for reporting varying metrics of benefit, the use of adaptive trial design and adapted statistical analyses. The authors also warned that eligibility criteria for patients into trials will need to be reassessed as disease burden has been impacted by pandemic measures.

The full paper, ‘Modeling the disruption of respiratory disease clinical trials by non-pharmaceutical COVID-19 interventions’, can be found here.

For more information, please contact:

Novadiscovery
François-Henri Boissel, Chief Executive Officer
Email: contact@novadiscovery.com

Consilium Strategic Communications 
Sukaina Virji, Kris Lam, Isabelle Abdou
Email: novadiscovery@consilium-comms.com

About Novadiscovery

Novadiscovery is a leading health tech company using in silico clinical trials to predict drug efficacy and optimize clinical trial development. The Company aims to improve R&D productivity and maximize patient outcomes by predicting the clinical benefit of a potential new drug candidate through computer simulation, ahead of human trials.

Novadiscovery’s innovative approach leverages disease modeling and simulation expertise accumulated over the past decade and combines mathematical models of diseases and potential new treatments with virtual patients in its integrated clinical trial simulation platform, JINKO®.

Novadiscovery is headquartered in Lyon, France and has a team of around 30 scientists, engineers & clinicians who work at the interface of biology, pharmacology, mathematics & computer science.

For more information, please visit https://www.novadiscovery.com and follow us on Twitter @novadiscovery and linkedin.com/company/novadiscovery

“Over my 12 years, it’s been a thrill to reach customers in 70+ countries, develop relationships with 1,400+ leading technology and global enterprises, and build a 55-person team running the top localization platform globally,” said founder Dimitris Glezos. “I am confident that PARC’s ambitious development plans and strategic vision will continue to accelerate the company’s growth and innovation for many years to come.”

Transifex was founded in response to emergent changes in software development and digital content creation that are now ubiquitous. Every company knows that having real-time conversations with customers in their own language creates lasting relationships and, regardless of whether the message is distributed through software, apps, or websites, the key is speed to market. Today all digital products share a common foundation of agile processes that require frequent iterations and constant updates, meaning localization must be embedded into the design and development processes from day one so that features and campaigns are launched at the same speed they are created. The traditional translation industry and its tools were not built to meet this need, so more companies are choosing to reach their customers globally by localizing their software and content with Transifex.

“We were immediately drawn to Transifex’s vision of making all software and content available in every language, and are very excited to assume leadership roles at the company. As the category-leading product enabling the global ambitions of digital-native companies, Transifex is poised for rapid growth alongside its customers,” said incoming CEO Chris Reese. Incoming President Tony Pilnik explained, “We see tremendous demand for a localization solution that sits seamlessly at the core of the tech stack and allows customers to translate their content in the most cost-effective method possible without slowing down the speed of creation.”

PARC brings considerable resources to Transifex including backing from leading financial institutions, including Pacific Lake Partners and Bridge Bank, and guidance from seasoned board members, including software industry veterans Bob Brennan and Dennis Dresser. The Transifex team remains intact and operations will stay centered around the United States and Greece in support of Transifex’s global customer base.

About Transifex

The Transifex SaaS platform enables companies of all sizes to reach their customers globally at scale with a local message. Its integrations and workflow automation let companies localize their software and digital content such as web and mobile apps, websites, games, video, help centers, subtitles, and more, enabling cost-effective language translation that doesn’t slow down the creation processes. Category leading companies like HubSpot, Quora, Strava and Klarna rely on Transifex to achieve a truly multilingual presence with ease.

Direct media inquiries to: panpap@transifex.com.

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Turin, 13 April 2022. Iveco Group (MI: IVG) announces that all the resolutions proposed by the Board of Directors to the Shareholders’ Annual General Meeting (“AGM”) held today were approved.

The AGM adopted the 2021 Company Financial Statements, released from liability the members of the Board, positively advised on the 2021 Remuneration Report and appointed Benoît Ribadeau-Dumas as non-executive director. His CV is posted on the Company’s website (www.ivecogroup.com).

In addition, Ernst & Young Accountants LLP was reappointed as the independent auditor of the Company for the 2022 financial year, Deloitte Accountants B.V. was appointed as the independent auditor of the Company for the 2023 financial year.

Finally, the plan to award (rights to subscribe for) common shares to executive directors in accordance with article 12.6 of the Company’s articles of association was approved.

Details of all matters discussed today by the AGM and the Chair’s and the Chief Executive Officer’s speeches are available on the Company’s website (www.ivecogroup.com). The voting results will be posted shortly.

Iveco Group N.V. (MI: IVG) is a global automotive leader active in the Commercial & Specialty Vehicles, Powertrain, and related Financial Services arenas. Each of its eight brands is a major force in its specific business: IVECO, a pioneering commercial vehicles brand that designs, manufactures, and markets heavy, medium, and light-duty trucks; FPT Industrial, a global leader in a vast array of advanced powertrain technologies in the agriculture, construction, marine, power generation, and commercial vehicles sectors; IVECO BUS and HEULIEZ, mass-transit and premium bus and coach brands; Iveco Defence Vehicles, for highly-specialised defence and civil protection equipment; ASTRA, a leader in large-scale heavy-duty quarry and construction vehicles; Magirus, the industry-reputed firefighting vehicle and equipment manufacturer; and IVECO CAPITAL, the financing arm which supports them all. Iveco Group employs approximately 34,000 people around the world and has 29 manufacturing plants and 31 R&D centres. Further information is available on the Company’s website: www.ivecogroup.com

Media Contacts:
Francesco Polsinelli, Tel: +39 335 1776091
Fabio Lepore, Tel: +39 335 7469007
E-mail: mediarelations@ivecogroup.com

Investor Relations:
Federico Donati, Tel: +39 011 0073539

E-mail: investor.relations@ivecogroup.com

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Collaboration to Forge DEA’s Ecosystem Accessibility From Astar Network

SINGAPORE, April 13, 2022 (GLOBE NEWSWIRE) — Today, Singapore-based GameFi platform provider Digital Entertainment Asset Pte. Ltd. (DEA) has inked a strategic partnership with Japan-based Astar Network to make its PlayMining ecosystem and associated products available on Astar’s Polkadot parachain. The new collaboration is designed to help expand Astar Network’s GameFi reach with the bevy of content and services already supported by DEA.

The PlayMining economic zone is purposefully designed and built for multi-chain distribution, helping the GameFi platform broaden its potential audience of users. DEA already features an audience of more than 2.3 million users spread across 100 countries, and forging relationships with blockchain networks will play a significant component in its future expansionary plans.

With the Astar tie-up, DEA will effectively be able to bridge its PlayMining economic zone, including play-to-earn (P2E) games, its DEAPcoin (DEP) native token, and even the NFT marketplace, while also attracting more users to Astar’s public blockchain. This will allow users to access GameFi directly from Astar Network and heighten the circulation of DEP, by extension

Astar Network, which features lower gas fees has worked hard to attract DeFi protocols. Already, the parachain has attracted more than $1 billion in total value locked (TVL), helping it compete with other major DeFi hubs. With the expansion into GameFi, the smart contract protocol will work to integrate DEA’s play-to-earn gaming content, which currently features four titles and another set for launch in the coming months.

■About Astar Network
Formerly known as Plasm Network, Astar Network was founded in 2021 in Japan as a smart contract protocol compatible with EVM and WASM. Now operating as a Polkadot parachain, Astar’s EVM and WASM compatibility help developers quickly migrate smart contracts and dApps from outside networks to benefit from the scalability, affordability, and ultra-low power consumption it features. Funded by Alameda Ventures, Binance, Coinbase, Gavin Wood, Huobi, OKX, and Polychain, the proof-of-stake blockchain technology focuses on sustainable development, underscored by its commitment to the dAppStaking strategy to incentivize developers.

More information about Astar Network can be found on its official website.

■About DEAPcoin (DEP)
DEAPcoin is a utility token that is distributed on DEA’s GameFi platform, PlayMining, and can be used to trade NFTs. PlayMining was launched on May 26, 2020, and as of January 2022 has over 2.3 million users in 100 countries worldwide.

On January 26, 2022, DEAPcoin was listed on BITPOINT, a crypto asset exchange licensed by the Japanese Financial Services Agency, becoming the 38th crypto asset handled in Japan. It is also the first Play to Earn token to be circulated in Japan and PlayMining is the world’s first Play to Earn token economy, leading the global GameFi market.

More information on DEAPcoin is available in the whitepaper.

■About Digital Entertainment Asset Pte. Ltd. 
DEA, a GameFi platform business, was founded in Singapore in August 2018, and is developing JobTribes, a Play to Earn game, and PlayMining NFT, an NFT marketplace. Using blockchain technology, the company aims to realize a world where one can create value by having fun.

Co-CEO: Naohito Yoshida, Kozo Yamada
Location: 7 Straits View, Marina One East Tower,#05-01,Singapore 018936
Establishment: August 2018
Business description: GameFi platform business

Contact Information
Digital Entertainment Asset Pte Ltd
Public Relation: Takasugi ｜tomoyuki_takasugi@dea.sg / Soeda｜soeda@dea.sg

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The LeddarEngine™ platform is powered by LeddarTech’s LCA3 SoC and state-of-the-art modular software, enabling improved sensor performance with the lowest development time

QUEBEC CITY, April 13, 2022 (GLOBE NEWSWIRE) — LeddarTech^®, a global leader in providing the most flexible, robust and accurate ADAS and AD sensing technology, is pleased to announce the availability of a completely new version of the LeddarEngine software to enable and accelerate LiDAR sensor development.

The LeddarEngine sets a new standard for developing highly integrated and flexible solid-state LiDAR solutions optimized for high-volume production. This complete solution comprises the LeddarCore™ LCA3 system on chip (SoC) and LeddarSP™ signal processing.

This new version specifically introduces several new integration tiers for the LeddarEngine software and compatibility with new hardware platforms. LeddarTech is introducing a separation of the control, signal processing and point-cloud processing, which can be used independently or in combination, enabling customers to maintain greater control over their final solution.

LiDAR developers that presently have signal processing toolchains implemented for their current products will benefit from using only the control kernel for easier and faster integration of the LeddarCore into their next-generation products. Tier 1-2s, system integrators and new LiDAR makers will still benefit from the complete offering by leveraging LeddarTech’s proprietary signal processing and expertise.

This version of the LeddarEngine is compatible with Xilinx Zynq UltraScale+ MPSoC, in addition to the already supported Renesas R-Car SoC. Furthermore, the porting to other platforms and operating systems is now easier than ever, thanks to this new modular architecture which improves the separation of hardware and software.

Key Benefits

• Easier integration into existing architectures, enabling retrofit to improve cost, power consumption and size
• Enables Tier 1-2s and LiDAR makers to leverage existing signal processing toolchain and to develop their algorithms
• Support for new hardware platforms and easier porting to new operating systems
• Fully scalable and modular software offering available to accelerate development and time-to-market

“Over the past 15 years, LeddarTech has been a leader in developing sensing solutions that support our customers in developing ADAS and AD products,” stated Mr. Charles Boulanger, CEO of LeddarTech. “The natural evolution of our LeddarEngine powered by our LCA3 SoC and especially our proprietary modular software enables our customers to even greater flexibility in design and to accelerate their development time, leading to lower cost and a faster path to revenue,” concluded Mr. Boulanger.

About LeddarTech

Founded in 2007, LeddarTech is a comprehensive end-to-end environmental sensing company that enables customers to solve critical sensing, fusion and perception challenges across the entire value chain. LeddarTech provides cost-effective perception solutions scalable from Level 2+ ADAS to Level 5 full autonomy with LeddarVision™, a raw-data sensor fusion and perception platform that generates a comprehensive 3D environmental model from a variety of sensor types and configurations. LeddarTech also supports LiDAR manufacturers and Tier 1-2 automotive suppliers with key technology building blocks such as LeddarSteer™ digital beam steering and the LiDAR XLRator™, a development solution for automotive-grade solid-state LiDARs based on the LeddarEngine™ and core components from global semiconductor partners. The company is responsible for several innovations in cutting-edge automotive and mobility remote-sensing applications, with over 100 patented technologies (granted or pending) enhancing ADAS and autonomous driving capabilities.

Additional information about LeddarTech is accessible at www.leddartech.com and on LinkedIn, Twitter, Facebook and YouTube.

Contact:
Daniel Aitken, Vice-President, Global Marketing, Communications and Investor Relations, LeddarTech Inc.
Tel.: + 1-418-653-9000 ext. 232 daniel.aitken@leddartech.com

Investor relations contact: InvestorRelations@leddartech.com
https://investors.leddartech.com/

Leddar, LeddarTech, LeddarSteer, LeddarEngine, LeddarVision, LeddarSP, LeddarCore, LeddarEcho, VAYADrive, VayaVision, XLRator and related logos are trademarks or registered trademarks of LeddarTech Inc. and its subsidiaries. All other brands, product names and marks are or may be trademarks or registered trademarks used to identify products or services of their respective owners.

More than 60 high profile strategic investors believe Web3 will transform art, fan engagement, intellectual property & creative value

USA, April 13, 2022 (GLOBE NEWSWIRE) — APRIL 13th, 2022 — MIAMI:  Today, MoonPay, the leading global crypto payments infrastructure provider, announced that more than 60 influential figures and organizations from the worlds of music, sports, media & entertainment have collectively invested $87 million in the company. The strategic investors represent industries on the cusp of transformation by Web3 technology, which is changing the way creatives, artists, and athletes approach art, fan engagement, and intellectual property management.

Named investors include the following (in alphabetical order by first name):

Anthony Kiedis of the  Red Hot Chili Peppers Ashton Kutcher and Guy Oseary’s Sound Ventures Austin Rosen’s Electric Feel Ventures BLOND:ISH Brent Faiyaz & Jayne Andrews,Ty Baisden Brie Larson* Bruce Willis Connect Ventures David Grutman Dimitri Vegas & Like Mike Diplo Drake & Adel ‘Future’ Nur’s Dreamcrew Eric Eisner* Eva Longoria Gal Gadot Gee Roberson G-Eazy Gibson Hazard

Gwyneth Paltrow & Moj Mahdara’s Kinship Ventures James Corden Jamil Davis and Matt Bauerschmidt’s Revels Group Ventures Jason Derulo Justin Bieber K5 Global Kate Hudson Katie McGrath* Kevin and Rick Yorn’s BroadLight Capital Kimberly Blackwell* Larry Gagosian Lil Baby Lil Durk Marc Benioff’s TIME Ventures Marcy Venture Partners Maria Sharapova Matte Babel Matthew McConaughey Michael Ovitz Mindy Kaling* Nancy Twine*

Palm Tree Crew Paris Hilton Paul George PLUS Capital Post Malone Questlove* Ryan Tedder of One Republic Sam Feldt Scooter Braun Shailene Woodley* Shawn Mendes, FEWOCiOUS & Andrew Gertler’s AG Ventures Shay Mitchell Snoop Dogg & Nick Adler, Karan Wahder, Champ Medici Stacey Bendet* Steve Aoki & Matt Colon The Chainsmokers’ Mantis VC The Weeknd & Amir “Cash” Esmailian Trina Spear* Yara Shahidi, Keri Shahidi, Afshin Shahidi* Zoe Saldaña*

* Kinship Ventures LP

From Entertainment:

“NFTs and Web3 technology will revolutionize the business of entertainment,” said Michael Ovitz, co-founder at CAA, and former President at The Walt Disney Company.  “Consumers are seeking new ways to consume entertainment and engage with their favorite creators — and the creators themselves want different ways of owning and sharing their creative output. MoonPay is helping to power that change as it lowers the barrier of entry to the crypto economy, and I’m excited to join them on that journey.”

“Web3 is inspiring the entertainment industry, and commerce in general, to reimagine the way we create community, connect with fans, build value and manage intellectual property,” said Gwyneth Paltrow, Co-Founder of Kinship Ventures. “We are excited to invest in MoonPay because we believe their technology is best positioned to make participating in cryptocurrency more accessible.”

“Crypto and NFTs are critical components in the growth and development of the creator economy,“ said Guy Oseary, Co-Founder of Sound Ventures. “As creators more consciously carve out their space and communities in Web3, MoonPay’s innovative platform is a bridge between the status quo and the future. MoonPay is an accelerator for industry-changing ideas, and I’m excited to see what comes next.”

From Sports

“In the ever-changing sports landscape, it’s important to keep an eye toward the future,” said Paul George, seven-time NBA All Star and Olympic Gold Medalist. “Crypto and NFTs will be key to maximizing the business of professional sports as we look ahead, and I’m excited to be a key contributor as one of MoonPay’s strategic investors.”

From Music

“NFTs and Web3 are the next frontiers of where music is going,” said Steve Aoki, Grammy-nominated DJ, producer, and founder of A0K1VERSE. “Whether you’re a musician or a creator, this technology will expand your reach and the way you connect with fans more deeply. It won’t be enough to release new drops and hope it works; you’ve got to be way more participatory. Web3 makes that possible. I’m excited to invest in MoonPay because I think they will play a vital role in moving all of this forward.”

“Web3 is radically changing the way we approach the business of entertaiment, sports and music,” said Ivan Soto-Wright, CEO and Co-founder of MoonPay. “Hollywood is using smart contracts and blockchain technology to assert their creative intellectual property rights. Major global sports franchises have used digital tokens and NFT collectibles to transform fan engagement. And recording artists are beginning to explore how NFTs can give them more control over royalty rights. These are the underpinnings of a creator economy renaissance. And our strategic investors are helping to lead that movement. We’re honored to work with them to help onboard the world to Web3.”

Notes to Editors

MoonPay’s suite of payments infrastructure products provides a seamless way for people to buy and sell cryptocurrencies and NFTs. It brings the easy-to-use experience consumers have come to demand from traditional e-commerce to Web3. Ten million customers across 160 countries have processed close to $3 billion in transactions on the MoonPay platform through more than 250 partner sites, including Bitcoin.com and OpenSea.

MoonPay’s $555 million Series A financing round led by Tiger Global Management and Coatue with participation from Blossom Capital, Thrive Capital, Paradigm, and NEA valued the company at $3.4 billion. The funding has allowed MoonPay to grow its global footprint through new products like NFT Checkout and MoonPay Concierge, and through new partnerships with leading organizations like OpenSea, Michael Jordan’s “Heir Jordan,” Tom Brady’s Autograph, and FaZe Clan.

About MoonPay

MoonPay is the world’s leading global crypto payments infrastructure provider. Leading marketplaces worldwide are providing their users with a simpler way to buy and sell NFTs using MoonPay’s industry-first NFT Checkout solution, which allows the purchase of NFTs instantly with a credit or debit card. The company is active in more than 160 countries and is trusted by 250+ leading wallets, websites, and applications.

For more information, visit: https://www.moonpay.com

Media
MoonPay
media@moonpay.com