Read about NYCREC at www.nycrec.io

NEW YORK, Sept. 06, 2018 (GLOBE NEWSWIRE) —  New York City Real Estate Coin (NYCREC), a tokenized real estate fund that allows token holders to enjoy the benefits of fractional ownership of real estate in New York City, has just announced that its Regulation S* securities token offering (STO) will begin in Q4 2018.

What is New York City Real Estate Coin?

NYCREC is the world’s first tokenized real estate fund focused on New York City real estate with an institutional-quality real estate and financial management team at the helm. It aims to give NYCREC token holders the following benefits:

• Regular dividends from the cashflow of the properties in the NYCREC portfolio, distributed in the form of Ethereum (ETH) airdrops to token holders
• Managed portfolio of real estate with greater flexibility and diversification than a similar real estate investment trust (REIT), which is typically narrower in its scope of investments
• Lower expense fees than a similar real estate investment trust (REIT), leading to more pass-through profits for token holder
• Independent financial reports on progress of the project and its finances after the ICO is completed
• Increased accessibility to New York City real estate for the international community

The long-term vision of the project is to tokenize real estate in major gateway cities around the world and to build a dedicated, collateralized blockchain for asset-backed security token offerings.

The Team Behind New York City Real Estate Coin

The NYCREC has managed or invested over $15 billion in real estate projects in New York City and other major gateway cities worldwide over a 21-year career with a risk-adjusted, year-over-year internal rate of return of up to 25%.

The team is decorated with Wall Street investment professionals, including Chief Executive Officer Alain Oberrotman, former Worldwide Controller at McKinsey; Chief Blockchain Officer Neil Benedict, former Head of Product Development at BANKEX; Chief Operations Officer Paul Brownstein, who recently bought a $100mm NPL (Non-Performing Loan) portfolio; Charles Wyman, Chief Investment Officer and former Head of Global Credit Research at PIMCO; and Principal Steven Wasserman, Senior Advisor to a $4 billion NYC-based hedge fund. Advisors to the team include Leonard Seelig, Executive Director of BABB and Serg Gulko, CEO of XTRD.

To learn more about NYCREC, join the Telegram community (https://t.me/nycrec), follow them on Twitter @NYCRECoin, or email info@nycrec.io.

*NYCREC Tokens will only be offered by New York City Real Estate Coin to non-US persons in compliance with the registration provided by Regulation D and Regulation S of the United States Securities Exchange Act.

About NYCREC
NYCREC is a tokenized real estate fund for New York City real estate with lower expense fees and greater diversification than a similar real estate investment trust (REIT). NYCREC Token holders will have the ability to receive dividends from the cashflow of the NYCREC portfolio in the form of Ethereum (ETH) airdrops. The team has managed or invested over $15 billion in real estate over their careers, with up to a 25% year-over-year risk-adjusted internal rate of return.

Contact
Steven Wasserman, Principal info@nycrec.io

 docQbot combines AI and HotDocs’ document assembly technology to help international companies do business with Chinese entities

SAN DIEGO, Sept. 06, 2018 (GLOBE NEWSWIRE) — HotDocs, an AbacusNext product and the global leader in document automation software, today announced its partnership with legal services provider, docQbot (Beijing docQbot Huiwen Data Technology Co., Ltd, a sister company of China Going Global Think-tank (“CGGT”)). HotDocs’ industry leading document automation technology will power docQbot’s recently launched bilingual contract drafting tool designed to aid organizations conducting international business with Chinese entities.

Currently in beta release, docQbot’s online contract service offers twenty fully automated, intelligent, contract templates. Each bilingual template can in many cases create hundreds of thousands or even millions of contract variations in both English and Chinese.  docQbot also is working with top law firms around the world to localize the base templates to support business transactions in more than 100 countries.

Templates available through the docQbot platform were designed by legal experts with a deep understanding of the Chinese market and the complexities associated with business negotiations. Gary Eunson, International Sales Director at AbacusNext, stated, “This docQbot solution is unique in that it combines artificial intelligence with HotDocs document automation technology to support the creation of multi-language documents in a very innovative way. This specialized consumer-facing application is the first of its kind and expands on the possibilities of what’s possible with document automation technology within the global marketplace. Businesses that tap into this contract generation tool will find that it simplifies so many of their challenges associated with complex international trade agreements.”

The contract generation tool is ideally suited for organizations conducting business with Chinese entities associated with outbound investments and foreign trade transactions. The easy-to-use interface makes it possible for legal professionals to quickly generate high-quality business contracts suited to early stage negotiations. Contracts can be created in as little as 10-15 minutes.

Mary Bai, co-founder and CEO of docQbot and CGGT, stated, “CGGT is very excited to team up with its sister company, docQbot, and with HotDocs to provide this unique legal AI solution to help both Chinese outbound investors and foreign trade companies avoid common problems and achieve more success in their cross-border deals. The docQbot tool makes it simple and easy to do contracts the right way. It is fast and low cost.”

docQbot also understands that most business contracts require additional expert counsel to address the unique aspects of each business arrangement. As such, docQbot can draw upon its close relationships with law firms in more than 100 countries to provide users with legal advice reaching beyond the scope of the docQbot tool. This allows Chinese and foreign trade companies to access in-country expertise needed to successfully conduct business internationally.

About HotDocs
HotDocs is the global industry leader in document automation technology, with customers in 60 countries and over one million users.  Document automation enables a vast reduction in time spent in the production of high volume, repeat documentation such as lending packages, credit documentation, and client on-boarding. Widely used within the banking, insurance, legal, government, and corporate sectors, HotDocs software helps to increase accuracy, reduce cost, eliminate risk, and improve efficiency in the generation of complex, or simple, repeat documentation.

For more information, visit www.hotdocs.com or connect with HotDocs on its blog, and on Twitter, LinkedIn or Facebook.

About AbacusNext
As the largest Technology-as-a-Service (TaaS) provider for the professional services sector, AbacusNext helps legal and accounting professionals achieve ultimate success and peace of mind through the delivery of a complete suite of compliance-ready technology solutions designed to support a secure and cloud-enabled practice at a cost they can afford. Its portfolio of turnkey solutions includes hardware, software, and infrastructure on a pay-as-you-go model; Practice Management, Client Resource Management (CRM), Payment Processing, Email, Desktop-as-a-Service (DaaS), and Managed IT.

For more information, visit www.abacusnext.com or connect with AbacusNext on its blog, and on Twitter, LinkedIn or Facebook.

About docQbot and CGGT
CGGT operates the China Going Global Think-tank platform, which provides Chinese enterprises with professional information and reports on outbound investment, covering strategy, finance, accounting, valuation, law, risk management, human resources, tax, and data and brand management. The docQbot solution is designed to help Chinese companies avoid common problems and achieve a greater level of success in both ODI and foreign trade transactions. All contracts are available in English and/or Chinese versions and are being localized for use in up to 100 countries and territories around the world. Just answer a few simple questions, and docQbot can produce a high-quality dual-language draft contract customized for your transaction in just a few minutes! Moreover, if you need offline support from qualified legal advisors, you will also be able to draw upon docQbot’s extensive network of leading lawyers across China and around the world. To learn more about docQbot and CGGT, visit www.cggthinktank.com and www.docqbot.com/en.

Contact:
858-529-0018
press@abacusnext.com

6 of 8 pts (75%) ORR in treatment-naïve EGFR mutation-positive NSCLC patients

Well-tolerated with unremarkable safety profile; No DLTs or related SAEs

Phase 3 trial in treatment-naïve EGFR mutation-positive NSCLC patients targeted to commence in 2019

NEW YORK, Sept. 06, 2018 (GLOBE NEWSWIRE) — Checkpoint Therapeutics, Inc. (“Checkpoint”) (NASDAQ: CKPT), a clinical-stage immuno-oncology biopharmaceutical company focused on the acquisition, development and commercialization of novel treatments for patients with solid tumor cancers, today announced positive preliminary safety and efficacy data from an ongoing Phase 1/2 clinical trial of CK-101 (also known as RX518), a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) being evaluated in advanced non-small cell lung cancer (NSCLC). The data will be presented on Monday, Sept. 24, at 10:30 a.m. ET in a late-breaking oral presentation at the International Association for the Study of Lung Cancer (IASLC) 19th World Conference on Lung Cancer in Toronto.

“These preliminary data demonstrate CK-101 is well-tolerated at the doses tested while also demonstrating encouraging anti-tumor activity, particularly in treatment-naïve EGFR mutation-positive lung cancer patients,” said Melissa L. Johnson, M.D., Associate Director, Lung Cancer Research, Sarah Cannon Research Institute at Tennessee Oncology, PLLC, and study chair of the Phase 1/2 trial.

“The data to date demonstrate CK-101’s potential to be a highly effective mutant-selective EGFR inhibitor with the potential for a differentiated safety profile,” said James F. Oliviero, President and Chief Executive Officer of Checkpoint Therapeutics. “We look forward to continuing to advance CK-101 towards a pivotal Phase 3 trial next year, positioning CK-101 to potentially be only the second third-generation EGFR inhibitor to enter the market.”

The first-in-human, multicenter trial is evaluating CK-101 in NSCLC patients with EGFR mutations and other advanced malignancies (NCT02926768). Following dose escalation ranging from 100 mg to 1,200 mg/day in patients with any solid tumor where targeted EGFR was deemed reasonable, a first dose-expansion cohort was enrolled at 400 mg twice daily in patients with a confirmed diagnosis of either (1) EGFR mutation-positive advanced or metastatic NSCLC without prior exposure to EGFR-TKI therapy, or (2) T790M-positive advanced or metastatic NSCLC with disease progression on previous EGFR-TKI therapy. There was no limit on the number of prior lines of systemic therapy patients received prior to entering the study.

Key Data from the Abstract

As of June 2018, 37 patients had been treated with CK-101 in dose escalation and dose-expansion cohorts and were evaluable for safety.

• No dose limiting toxicities (DLTs) or treatment-related serious adverse events (SAEs) were reported.
• The most common drug-related treatment-emergent adverse events (>10%) included nausea (16%), diarrhea (14%), lacrimation increased (14%) and vomiting (11%).

In dose-expansion, 19 EGFR mutation-positive NSCLC patients were treated with CK-101 at a dose of 400 mg twice daily and were evaluable for response (RECIST v1.1). Eight patients achieved a partial response (7 confirmed, 1 pending).  Additional efficacy findings include:

• In eight treatment-naïve patients, six patients (75%) achieved a partial response.
• In six patients with brain metastases present at baseline, three patients achieved a partial response.
• Higher drug exposures were associated with a higher response rate with a confirmed objective response rate (ORR) of 55% (6/11) in patients achieving a maximum serum concentration (Cmax) greater than 400 ng/mL.
• 100% (19/19) disease control rate was observed, with 84% (16/19) of patients experiencing target lesion reduction versus baseline.
• Median duration of response and progression-free survival were not reached as of the data cutoff.

Enrollment in the trial is ongoing to identify the optimal dose to maximize therapeutic effect.

Oral Presentation

Details of the oral presentation at the IASLC 19th World Conference on Lung Cancer are as follows:

Title: CK-101 (RX518), a Third Generation Mutant-Selective Inhibitor of EGFR in NSCLC: Results of an Ongoing Phase I/II Trial
Date / Time: Monday, Sept. 24, 2018 at 10:30am
Session: Novel Therapies in ROS1, HER2 and EGFR
Presenter: Melissa L. Johnson, M.D., Associate Director, Lung Cancer Research, Sarah Cannon Research Institute at Tennessee Oncology, Nashville, Tenn.

The full abstract can be found on the conference website and is also available on the Publications page in the Pipeline section of Checkpoint’s website, www.checkpointtx.com.

About CK-101

CK-101 (also known as RX518) is an oral, third-generation, irreversible kinase inhibitor against selective mutations in the EGFR gene. Activating mutations in the tyrosine kinase domain of EGFR, such as L858R and exon 19 deletion, are found in approximately 20 percent of patients with advanced non-small cell lung cancer (NSCLC).

Compared to chemotherapy, first-generation EGFR inhibitors significantly improved objective response rate and progression-free survival in previously untreated NSCLC patients carrying EGFR mutations. However, tumor progression could develop due to resistance mutations, often within months of treatment with first-generation EGFR inhibitors. The EGFR T790M “gatekeeper” mutation is the most common resistance mutation found in patients treated with first-generation EGFR inhibitors. The mutation decreases the affinity of first-generation inhibitors to EGFR kinase domain, rendering the drugs ineffective. Second-generation EGFR inhibitors have improved potency against the T790M mutation, but have not provided meaningful benefits in NSCLC patients due to toxicity from also inhibiting wild-type EGFR. Third-generation EGFR inhibitors are designed to be highly selective against both EGFR-TKI-sensitizing and resistance mutations, with minimal activity on wild-type EGFR, thereby improving tolerability and safety profiles.

Checkpoint Therapeutics is developing CK-101 for the treatment of NSCLC patients carrying the susceptible EGFR mutations. These include the EGFR T790M mutation in second-line NSCLC patients, as well as the EGFR L858R and exon 19 deletion mutations in first-line NSCLC patients.

Checkpoint holds an exclusive worldwide license (except with respect to certain Asian countries) to CK‐101, which it acquired from NeuPharma, Inc., in 2015.

About Checkpoint Therapeutics

Checkpoint Therapeutics, Inc. (“Checkpoint”) is a clinical-stage, immuno-oncology biopharmaceutical company focused on the acquisition, development and commercialization of novel treatments for patients with solid tumor cancers. Checkpoint is evaluating its lead small-molecule, targeted anti-cancer agent, CK-101, in a Phase 1/2 clinical trial for the treatment of patients with EGFR mutation-positive non-small cell lung cancer (NSCLC). In addition, Checkpoint is currently evaluating its lead antibody product candidate, CK-301, an anti-PD-L1 antibody licensed from the Dana-Farber Cancer Institute, in a Phase 1 clinical trial in checkpoint therapy-naïve patients with selected recurrent or metastatic cancers. Checkpoint plans to develop CK-301 as a treatment for patients with NSCLC and other solid tumors. Checkpoint, a Fortress Biotech company, is headquartered in New York City. For more information, visit www.checkpointtx.com.

About Fortress Biotech

Fortress Biotech, Inc. (“Fortress”) (NASDAQ: FBIO) is a biopharmaceutical company dedicated to acquiring, developing and commercializing novel pharmaceutical and biotechnology products. Fortress develops and commercializes products both within Fortress and through certain of its subsidiary companies, also known as Fortress Companies. In addition to its internal development programs, Fortress leverages its biopharmaceutical business expertise and drug development capabilities and provides funding and management services to help the Fortress Companies achieve their goals. Fortress and the Fortress Companies may seek licensing arrangements, acquisitions, partnerships, joint ventures and/or public and private financings to accelerate and provide additional funding to support their research and development programs. For more information, visit www.fortressbiotech.com.

Forward‐Looking Statements

This press release may contain “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, each as amended. Such statements include, but are not limited to, any statements relating to our growth strategy and product development programs, and any other statements that are not historical facts. Forward-looking statements are based on management’s current expectations and are subject to risks and uncertainties that could negatively affect our business, operating results, financial condition and stock value. Factors that could cause actual results to differ materially from those currently anticipated include: risks relating to our growth strategy; our ability to identify doses of CK-101 that increase drug exposure at safe levels; our ability to commence a Phase 3 trial for CK-101 in 2019; our ability to obtain, perform under and maintain financing and strategic agreements and relationships; risks relating to the results of research and development activities; risks relating to the timing of starting and completing clinical trials; uncertainties relating to preclinical and clinical testing; our dependence on third-party suppliers; our ability to attract, integrate and retain key personnel; the early stage of products under development; our need for substantial additional funds; government regulation; patent and intellectual property matters; competition; as well as other risks described in our SEC filings. We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our expectations or any changes in events, conditions or circumstances on which any such statement is based, except as required by law.

Company Contact:
Jaclyn Jaffe
Checkpoint Therapeutics, Inc.
(781) 652-4500
ir@checkpointtx.com

Investor Relations Contact:
Jeremy Feffer
Managing Director, LifeSci Advisors, LLC
(212) 915-2568
jeremy@lifesciadvisors.com

Media Relations Contact:
Laura Bagby
6 Degrees
(312) 448-8098
lbagby@6degreespr.com